The Midwest might have Route 66, but I think many of the places and people along U.S. Highway 78 in South Carolina make for a great day trip that will take you all the way to Charleston!

Blackville
There are two stops I recommend. One is in town, the other a few miles off 78 on Highway 3.

Miller’s Breadbasket – Amish/Mennonite Home Cooking

God’s Healing Springs – If you like COLD water and history this is worth the visit. Bring a cooler and get in line!

God's Acre Healing Springs, Blackville, South Carolina
The land's owner is listed as "God, Almighty" in local property records, so its water comes straight from Jehovah. Locals return frequently to replenish their supply of healing liquid.
Denmark
Jim Harrison Gallery – Stop in and check out some of his original paintings as well as prints from Mr. Harrison’s more than thirty-year career as an artist. It’s easy to find on South Main Street
Branchville
The Churn- This place has been around since I was a kid! The best for lunch or dessert!
St. George
World Grits Festival- I took these a few years ago when we visited the parade. Rolling in the grits get REAL in St. George!
Summerville
We called Summerville home for 10 years. Flowers, Sweet Tea and High School Football!